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Current areas of research for this peptide include: • Binding affinity across MC1R, MC3R, MC4R, and MC5R • Receptor-mediated cAMP responses • Differences in potency and receptor selectivity • Cyclic peptide conformation • Amino-acid substitutions and structural analogues • Structure–activity relationships • Melanocortin assay development • Comparison with more selective receptor ligands During an experiment, Dr