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Keywords: nose to brain delivery system, lipid based nanoparticle, in situ gel, bypassing BBB Introduction Global healthcare data indicate a significant increase in the prevalence of central nervous system (CNS) diseases, which contribute approximately 6–8% to the global economy

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Do not wait for routine labs Severe abdominal pain, persistent vomiting, signs of dehydration, fainting, allergic symptoms, or severe low-glucose symptoms need medical review