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In some embodiments, the Q-tag comprises a peptide selected from the group consisting of SEQ ID NOS: 6-18

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Dual agonism with GLP-1 and amylin As WL with GLP-1 RA and amylin analogues results both from distinct and overlapping pathways, a combination of these entero-pancreatic hormones may induce a synergistic WL effect [84]