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Although glutathione reductase activity was not significantly different between the groups, fish oil supplementation resulted in a smaller increase in GR compared with the control group, suggesting a possible antioxidant effect of fish oil supplementation

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Furthermore, treatments that target the interaction between PNPLA3 and ABHD5 (70) or the degradation of PNPLA3 (74) could be of therapeutic benefit to patients that carry the PNPLA3 I148M variant